Receptors exist throughout the body and are a substance to which endocannabinoids bind; Enzymes appear in many forms, but only two types of enzymes break down endocannabinoids, and Endocannabinoids complement the body by keeping internal functions running smoothly. Understanding the effects of CBD involves examining the relationship between the receptors and endocannabinoids.
There are two types of receptors: CB1 and CB2. CB1 receptors are primarily in the central nervous system and are responsible for governing coordination, movement, pain, appetite, memory, mood, and other functions. The CB2 receptors are in the peripheral nervous system, influencing pain, and inflammation.
After the enzymes break down the cannabinoids, the endocannabinoids look to bind with receptors. Researchers believe that CBD does not directly attach itself to the receptor but influences it in some way. Activating these receptors is what allows for many of the health benefits that people associate with the compound.
CBD can also influence non-cannabinoid receptors. According to Teaera Roland of Lotus Health, CBD modulates the 5ht serotonin receptor, which can treat psychotic disorders. It can also affect the TRPV1 receptor, which is responsible for pain and inflammation
